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Image Search Results
Journal: Biomaterials Research
Article Title: Metabolic Gadolinium Labeling of Clostridium novyi -Nontoxic for Magnetic Resonance Imaging Visualization of Spores and Germinated Bacteria
doi: 10.34133/bmr.0326
Figure Lengend Snippet: In vivo MRI tracking of Gd-spores in an orthotopic liver tumor model. (A) In vivo experimental schedule for N1S1 tumor implantation, intra-arterial administration of Gd-spores (10 8 /ml, prepared with 10 mM GdCl 3 ), and MRI. (B) Representative T1-weighted (T1W) and T2-weighted (T2W) MR images showing dynamic changes in tumor contrast following intra-arterial infusion of Gd-spores. (C) Tumor signal-to-noise ratio (SNR) and (D) contrast-to-noise ratio (CNR) on T1-weighted MR images up to 9 days ( n = 3). Data are presented as mean ± SD (* P < 0.05, *** P < 0.001, **** P < 0.0001).
Article Snippet:
Techniques: In Vivo, Tumor Implantation
Journal: World Journal of Hepatology
Article Title: Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement
doi: 10.4254/wjh.v17.i12.115551
Figure Lengend Snippet: Representative high-frequency ultrasound–based monitoring of orthotopic hepatocellular carcinoma established using the rat hepatoma cell line (N1S1). Tumor volume measurements obtained by ultrasound demonstrate an excellent correlation with reference histological and volumetric assessments ( r = 0.998, P < 0.001; Devan et al ), underscoring the accuracy, reproducibility, and experimental utility of this imaging approach for preclinical tumor evaluation. CT: Computed tomography; HCC: Hepatocellular carcinoma; 3D: Three dimensional; 3R: Replacement, reduction, and refinement. Created in BioRender ( www.biorender.com ).
Article Snippet: A syngeneic orthotopic HCC model was established in male Sprague
Techniques: Imaging, Computed Tomography